Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CL1_1158Phosphate transporter protein; COG0306. (403 aa)    
Predicted Functional Partners:
CL1_1159
Phosphate transport system regulator PhoU; COG1392.
 
  
 0.984
CL1_1157
COG1409.
       0.826
CL1_1260
Putative phosphate transport regulator; COG1392.
 
  
 0.790
CL1_1156
Hypothetical protein; COG1917.
       0.716
CL1_1160
ABC type transporter permease 1; COG0842.
     
 0.645
CL1_1161
ABC type transporter ATPase 2; COG1131.
     
 0.635
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.492
CL1_1162
Radical SAM domain protein; COG0641.
       0.443
CL1_1898
Amino acid transporter; COG0531.
  
  
 0.437
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
     
 0.400
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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