STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1176SAM-dependent methyltransferase 1; COG2521. (286 aa)    
Predicted Functional Partners:
CL1_1177
Hypothetical protein containing peptidase_M19 domain; COG2355.
       0.718
CL1_1178
Hypothetical protein; COG0457.
       0.696
CL1_1179
Hypothetical protein; COG1772.
 
     0.597
CL1_1410
Hypothetical protein; COG1542.
  
     0.545
CL1_1180
Signal peptidase I; COG0681.
       0.533
CL1_1313
Replication factor C small subunit; COG1372.
  
     0.518
CL1_0159
Putative RNA-binding protein containing THUMP domain; COG1818.
  
     0.438
CL1_1700
Hypothetical protein.
  
     0.426
CL1_0188
Molybdenum cofactor biosynthesis protein A1; COG2100.
  
     0.403
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.