STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1180Signal peptidase I; COG0681. (157 aa)    
Predicted Functional Partners:
CL1_1155
Putative signal peptidase I; COG0681.
  
  
  0.934
CL1_0754
Signal peptidase I, S26B family; COG0681.
     
  0.900
CL1_1179
Hypothetical protein; COG1772.
       0.818
CL1_1178
Hypothetical protein; COG0457.
  
  
 0.651
CL1_1177
Hypothetical protein containing peptidase_M19 domain; COG2355.
       0.645
leuS
leucyl-tRNA synthetase; COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
   
 0.568
CL1_1176
SAM-dependent methyltransferase 1; COG2521.
       0.533
CL1_0998
Hypothetical protein containing peptidase M50 domain 2; COG0750.
 
  
 0.527
CL1_0223
Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.
  
     0.512
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.512
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.