STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1194uracil-DNA glycosylase; COG1573. (189 aa)    
Predicted Functional Partners:
CL1_2022
Putative uracil-DNA glycosylase; COG1573.
  
  
 
0.921
CL1_1193
Hypothetical protein.
     
 0.895
CL1_0332
Archeal type N-glycosylase/DNA lyase; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates.
      
 0.888
CL1_1191
Hypothetical protein.
       0.810
CL1_1192
Hypothetical protein; COG1964.
       0.810
CL1_1195
Sodium/hydrogen antiporter, NhaC-type; COG1757.
       0.658
CL1_0706
Endonuclease IV; COG0648.
 
   
 0.488
CL1_1805
Pyruvate carboxylase subunit B; COG5016.
  
    0.450
CL1_1475
Glucose-1-phosphate thymidylyltransferase-like protein; COG1213; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.439
CL1_0542
Glutamate dehydrogenase; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.421
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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