STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1207Hypothetical protein; COG1233. (420 aa)    
Predicted Functional Partners:
CL1_1208
Carbamate kinase-like carbamoyl phosphate synthetase; COG0549; Belongs to the carbamate kinase family.
       0.813
CL1_1206
Aldehyde: ferredoxin oxidoreductase 2; COG2414.
 
     0.803
CL1_1209
Hypothetical protein; COG0616.
 
     0.631
CL1_1084
Phosphopantetheine adenylyltransferase; COG1019.
       0.625
CL1_1211
Hypothetical protein; COG1549.
 
     0.611
CL1_0563
Bifunctional short chain isoprenyl diphosphate synthase; COG0142; Belongs to the FPP/GGPP synthase family.
  
  
 0.575
CL1_1210
Hypothetical protein; COG1340.
       0.555
CL1_0407
Hypothetical protein containing SAM domain 3; COG1032.
 
  
 0.499
CL1_1896
Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family.
 
   
 0.494
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.435
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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