STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1211Hypothetical protein; COG1549. (568 aa)    
Predicted Functional Partners:
CL1_1210
Hypothetical protein; COG1340.
 
   
 0.944
CL1_0014
Hypothetical protein containing SAM domain 1; COG1244.
 
     0.786
CL1_1212
Hypothetical protein; COG0697.
       0.783
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
  
0.740
CL1_1213
Hypothetical protein; COG4031.
       0.723
CL1_0501
Putative nonsense-mediated mRNA decay protein, NMD3-family; COG1499.
  
     0.693
CL1_1740
Hypothetical protein; COG1326.
  
     0.676
CL1_1214
Hypothetical protein; COG3463.
 
     0.674
CL1_0646
Hypothetical protein containing metal dependent hydrolase domain; COG1831.
  
     0.672
CL1_1591
Hypothetical protein.
 
     0.671
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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