Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1212Hypothetical protein; COG0697. (345 aa)    
Predicted Functional Partners:
CL1_1211
Hypothetical protein; COG1549.
       0.792
CL1_1210
Hypothetical protein; COG1340.
       0.782
CL1_1213
Hypothetical protein; COG4031.
       0.671
CL1_1214
Hypothetical protein; COG3463.
       0.558
CL1_1209
Hypothetical protein; COG0616.
       0.487
CL1_1208
Carbamate kinase-like carbamoyl phosphate synthetase; COG0549; Belongs to the carbamate kinase family.
       0.403
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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