Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1228Universal stress protein 1; COG0589. (278 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.
  
    0.840
CL1_1225
Putative permease, DMT family 1; COG0697.
       0.602
CL1_1257
Putative methylated-DNA--protein-cysteine methyltransferase; COG0350.
  
  
 0.457
CL1_0816
Chaperonin subunit beta; COG0459; Belongs to the TCP-1 chaperonin family.
  
 
 0.450
engB
GTP-binding protein 1; Necessary for normal cell division and for the maintenance of normal septation.
   
 
 0.429
CL1_1226
Putative ATPase (AAA+ superfamily) 2; COG1672.
       0.416
CL1_0106
iron(II) transport system protein A; COG1918.
  
  
 0.414
CL1_1862
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.411
CL1_1626
AMP phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
  
    0.409
CL1_1037
Transcription regulator, ArsR family 7; COG0640.
     
 0.403
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.