STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_1233Hypothetical protein containing ribokinase-like domain 2; COG0524; Belongs to the carbohydrate kinase PfkB family. (296 aa)    
Predicted Functional Partners:
CL1_0467
Putative phospho-sugar mutase; COG1109.
 
 
 0.926
CL1_1398
ribose-1,5-Bisphosphate Isomerase; COG1184; Belongs to the eIF-2B alpha/beta/delta subunits family.
  
 
 0.926
CL1_0891
Phosphopentomutase; COG1109; Belongs to the phosphohexose mutase family.
  
 
 0.912
CL1_1232
Hypothetical protein containing ACT domain 2; COG2150.
       0.834
CL1_1234
Hypothetical protein; COG1653.
       0.820
hisA
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106.
  
    0.794
glkA
ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor.
  
   
 0.612
CL1_0365
Bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase; COG0794.
 
  
 0.579
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.533
pgk
Phosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family.
 
   
 0.531
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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