STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CL1_1238Nucleotide-binding protein, MRP family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (295 aa)    
Predicted Functional Partners:
CL1_1237
Hypothetical protein.
       0.818
CL1_1243
Pyruvate ferredoxin oxidoreductase subunit beta; COG1013.
     
 0.772
CL1_1244
Pyruvate ferredoxin oxidoreductase subunit alpha; COG0674.
     
 0.770
CL1_1245
Pyruvate ferredoxin oxidoreductase subunit delta; COG1144.
     
 0.763
CL1_1239
iron(III)-siderophore ABC transporter ATPase 1; COG1120.
     
 0.662
CL1_1247
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha; COG0674.
     
 0.643
CL1_1246
2-ketoisovalerate ferredoxin oxidoreductase subunit beta; COG1013.
     
 0.642
hypA
Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
   
   0.639
CL1_1248
2-ketoisovalerate ferredoxin oxidoreductase subunit delta; COG1144.
     
 0.635
CL1_1240
iron(III)-siderophore ABC transporter permease 1; COG0609.
     
 0.614
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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