STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1238Nucleotide-binding protein, MRP family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (295 aa)    
Predicted Functional Partners:
CL1_1239
iron(III)-siderophore ABC transporter ATPase 1; COG1120.
     
 0.646
CL1_1240
iron(III)-siderophore ABC transporter permease 1; COG0609.
     
 0.631
CL1_1241
iron(III)-siderophore ABC transporter ATP-binding protein; COG0614.
     
 0.599
CL1_1237
Hypothetical protein.
       0.598
CL1_1242
Formylmethanofuran dehydrogenase subunit E; COG2191.
  
    0.592
CL1_0200
NADH dehydrogenase subunit C; COG0852.
    
 0.578
CL1_0201
NADH dehydrogenase subunit D; COG0649; Belongs to the complex I 49 kDa subunit family.
     
 0.576
hypA
Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
   
   0.554
CL1_0640
NADH-quinone oxidoreductase subunit E; COG1905.
    
 0.539
CL1_0639
NADH-quinone oxidoreductase subunit F; COG1894.
    
 0.532
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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