STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1239iron(III)-siderophore ABC transporter ATPase 1; COG1120. (253 aa)    
Predicted Functional Partners:
CL1_1240
iron(III)-siderophore ABC transporter permease 1; COG0609.
 
 
 0.989
CL1_1241
iron(III)-siderophore ABC transporter ATP-binding protein; COG0614.
 
 
 0.987
CL1_1306
iron(III)-siderophore ABC transporter permease 2; COG0609.
 
 
 0.932
CL1_0137
Iron (III) ABC transporter periplasmic-binding protein; COG0614.
 
 
 0.912
CL1_1242
Formylmethanofuran dehydrogenase subunit E; COG2191.
 
    0.867
CL1_1238
Nucleotide-binding protein, MRP family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
     
 0.646
CL1_1243
Pyruvate ferredoxin oxidoreductase subunit beta; COG1013.
       0.478
CL1_1244
Pyruvate ferredoxin oxidoreductase subunit alpha; COG0674.
       0.475
CL1_1245
Pyruvate ferredoxin oxidoreductase subunit delta; COG1144.
       0.469
rpl2
50S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
     0.429
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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