STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1241iron(III)-siderophore ABC transporter ATP-binding protein; COG0614. (372 aa)    
Predicted Functional Partners:
CL1_1239
iron(III)-siderophore ABC transporter ATPase 1; COG1120.
 
 
 0.987
CL1_1240
iron(III)-siderophore ABC transporter permease 1; COG0609.
 
 
 0.985
CL1_1242
Formylmethanofuran dehydrogenase subunit E; COG2191.
 
    0.914
CL1_1305
iron(III)-siderophore ABC transporter ATPase 2; COG1120.
 
 
 0.892
CL1_1306
iron(III)-siderophore ABC transporter permease 2; COG0609.
 
 
 0.870
CL1_1238
Nucleotide-binding protein, MRP family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
     
 0.599
CL1_1243
Pyruvate ferredoxin oxidoreductase subunit beta; COG1013.
       0.493
CL1_1244
Pyruvate ferredoxin oxidoreductase subunit alpha; COG0674.
       0.489
CL1_1245
Pyruvate ferredoxin oxidoreductase subunit delta; COG1144.
       0.469
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
   
   0.436
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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