STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1242Formylmethanofuran dehydrogenase subunit E; COG2191. (231 aa)    
Predicted Functional Partners:
CL1_0794
Formate dehydrogenase subunit alpha FdhA; COG0243.
 
 
 0.928
CL1_1148
Formate hydrogen lyase subunit alpha; COG0243.
 
 
 0.928
CL1_1241
iron(III)-siderophore ABC transporter ATP-binding protein; COG0614.
 
    0.914
CL1_1147
Hypothetical protein containing ferredoxins domain 3; COG0437.
    
 0.902
CL1_1239
iron(III)-siderophore ABC transporter ATPase 1; COG1120.
 
    0.867
CL1_1240
iron(III)-siderophore ABC transporter permease 1; COG0609.
 
    0.859
CL1_0463
Cobalt ABC transport protein, CbiN; COG0310.
  
    0.703
CL1_0462
Cobalt ABC transporter permease, CbiM; COG0310.
 
    0.662
CL1_1238
Nucleotide-binding protein, MRP family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
    0.592
CL1_1245
Pyruvate ferredoxin oxidoreductase subunit delta; COG1144.
 
     0.539
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.