nac protein (Thermococcus cleftensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

nac

Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (111 aa)

Predicted Functional Partners:

rpl21e

0.959

rpl18e

0.947

rpl30

0.923

rpl18

0.921

rpl18a

0.920

rpl23

0.919

rpl19e

0.916

rps3ae

0.914

rpl24e

0.912

rpl34e

0.903

Your Current Organism:

Thermococcus cleftensis

NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
nac	rpl18	CL1_1253	CL1_0608	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	0.921
nac	rpl18a	CL1_1253	CL1_1575	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	50S ribosomal protein LX; COG2157.	0.920
nac	rpl18e	CL1_1253	CL1_0592	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	Ribosomal protein L18e; COG1727; Belongs to the eukaryotic ribosomal protein eL18 family.	0.947
nac	rpl19e	CL1_1253	CL1_0609	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	0.916
nac	rpl21e	CL1_1253	CL1_0283	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	50S ribosomal protein L21e; COG2139; Belongs to the eukaryotic ribosomal protein eL21 family.	0.959
nac	rpl23	CL1_1253	CL1_0626	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	50S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.	0.919
nac	rpl24e	CL1_1253	CL1_1743	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	50S ribosomal protein L24e; Binds to the 23S rRNA.	0.912
nac	rpl30	CL1_1253	CL1_0606	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	50S ribosomal protein L30; COG1841.	0.923
nac	rpl34e	CL1_1253	CL1_0601	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	Ribosomal protein L34Ae; COG2174; Belongs to the eukaryotic ribosomal protein eL34 family.	0.903
nac	rps3ae	CL1_1253	CL1_0160	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	30S ribosomal protein S3Ae; COG1890; Belongs to the eukaryotic ribosomal protein eS1 family.	0.914
rpl18	nac	CL1_0608	CL1_1253	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	0.921
rpl18	rpl18a	CL1_0608	CL1_1575	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	50S ribosomal protein LX; COG2157.	0.999
rpl18	rpl18e	CL1_0608	CL1_0592	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	Ribosomal protein L18e; COG1727; Belongs to the eukaryotic ribosomal protein eL18 family.	0.999
rpl18	rpl19e	CL1_0608	CL1_0609	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
rpl18	rpl21e	CL1_0608	CL1_0283	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	50S ribosomal protein L21e; COG2139; Belongs to the eukaryotic ribosomal protein eL21 family.	0.999
rpl18	rpl23	CL1_0608	CL1_0626	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	50S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.	0.999
rpl18	rpl24e	CL1_0608	CL1_1743	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	50S ribosomal protein L24e; Binds to the 23S rRNA.	0.999
rpl18	rpl30	CL1_0608	CL1_0606	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	50S ribosomal protein L30; COG1841.	0.999
rpl18	rpl34e	CL1_0608	CL1_0601	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	Ribosomal protein L34Ae; COG2174; Belongs to the eukaryotic ribosomal protein eL34 family.	0.999
rpl18	rps3ae	CL1_0608	CL1_0160	50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	30S ribosomal protein S3Ae; COG1890; Belongs to the eukaryotic ribosomal protein eS1 family.	0.999

page 1 of 6

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About