STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1256Hypothetical protein; COG0457. (343 aa)    
Predicted Functional Partners:
CL1_1257
Putative methylated-DNA--protein-cysteine methyltransferase; COG0350.
  
    0.823
CL1_1258
Putative tRNA/rRNA methyltransferase; COG0565.
       0.818
CL1_0754
Signal peptidase I, S26B family; COG0681.
 
  
 0.746
CL1_0223
Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.
  
 0.714
CL1_1259
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
 
     0.699
CL1_1260
Putative phosphate transport regulator; COG1392.
 
   
 0.675
CL1_1261
D-3-phosphoglycerate dehydrogenase; COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.645
CL1_0415
Phospho-sugar mutase-like protein; COG1109.
 
   
 0.637
CL1_0698
DNA polymerase, family B; COG0417.
 
 
 0.621
CL1_0920
Hypothetical protein; COG0535.
 
   
 0.595
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.