STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1258Putative tRNA/rRNA methyltransferase; COG0565. (235 aa)    
Predicted Functional Partners:
CL1_1256
Hypothetical protein; COG0457.
       0.818
CL1_1257
Putative methylated-DNA--protein-cysteine methyltransferase; COG0350.
       0.818
CL1_1259
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.651
CL1_1260
Putative phosphate transport regulator; COG1392.
       0.616
CL1_1261
D-3-phosphoglycerate dehydrogenase; COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.616
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.510
truB
H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
 
   
 0.486
CL1_1262
Fumarate hydratase subunit alpha; COG1951.
       0.464
CL1_1263
Fumarate hydratase subunit beta; COG1838.
       0.444
CL1_0764
Hypothetical protein containing methylase domain; COG2890.
     
 0.436
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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