Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_1302Threonine synthase 2; COG0498. (376 aa)    
Predicted Functional Partners:
CL1_1301
Putative dioxygenase; COG3885.
       0.916
CL1_1303
Hypothetical protein.
       0.916
CL1_0537
Threonine synthase 1; COG0498.
 
  
 
0.911
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
   
 
 0.910
CL1_0659
Homoserine dehydrogenase; COG0460.
 
 
 0.882
psmB-2
Proteasome subunit beta 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
       0.875
CL1_1305
iron(III)-siderophore ABC transporter ATPase 2; COG1120.
       0.807
CL1_1306
iron(III)-siderophore ABC transporter permease 2; COG0609.
       0.807
pdxS
Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
  
  
 0.736
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.729
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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