Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_1306iron(III)-siderophore ABC transporter permease 2; COG0609. (338 aa)    
Predicted Functional Partners:
CL1_1305
iron(III)-siderophore ABC transporter ATPase 2; COG1120.
 
 
 0.992
CL1_1239
iron(III)-siderophore ABC transporter ATPase 1; COG1120.
 
 
 0.896
CL1_0137
Iron (III) ABC transporter periplasmic-binding protein; COG0614.
 
 
 0.886
psmB-2
Proteasome subunit beta 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
       0.867
CL1_1302
Threonine synthase 2; COG0498.
       0.807
CL1_1303
Hypothetical protein.
       0.785
CL1_1241
iron(III)-siderophore ABC transporter ATP-binding protein; COG0614.
 
 
 0.710
CL1_1309
Hypothetical protein containing acyl-CoA N-acyltransferases (Nat)-domain; COG0456.
       0.698
endA
tRNA-splicing endonuclease subunit alpha; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
       0.698
CL1_1752
5'-3' nuclease; COG1630.
       0.634
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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