Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1342Hypothetical protein containing HAD-like domain 7; COG0463. (440 aa)    
Predicted Functional Partners:
CL1_1343
Hypothetical protein; COG2456.
     
 0.921
CL1_1341
Glycosyl transferase family 4 protein; COG0472.
 
  
 0.888
CL1_0354
Putative phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.749
pgk
Phosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family.
  
 
 0.733
glmS
Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
  
 0.711
CL1_0748
Glycosyl transferase family 2 protein 2; COG0463.
 
  
 0.706
CL1_0826
Hypothetical protein containing oxidoreductase-domain; COG0673.
 
  
 0.695
CL1_1795
UDP-glucose 4-epimerase; COG0451.
 
  
 0.690
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
     
 0.671
CL1_0841
Putative UDP- or dTTP-glucose 4-epimerase or 4-6-dehydratase; COG0451.
 
  
 0.664
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.