STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1353Hypothetical protein; COG2151. (177 aa)    
Predicted Functional Partners:
CL1_1352
Hypothetical protein; COG1365.
       0.851
CL1_1354
Putative ferredoxin; COG1141.
       0.818
bpsA
Putative methyltransferase; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
       0.793
CL1_0492
Putative cysteine desulfurase; COG0520.
 
  
 0.776
CL1_0150
ABC-type transport involved in Fe -S cluster assembly, ATPase component; COG0396.
 
  
 0.749
CL1_0149
ABC-type transport involved in Fe -S cluster assembly, permease component; COG0719.
 
   
 0.702
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
       0.558
CL1_1664
Cysteine synthase; COG0031.
     
 0.530
moaA
Molybdenum cofactor biosynthesis protein A2; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
     
 0.455
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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