STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1356Short-chain alcohol dehydrogenase; COG1028. (267 aa)    
Predicted Functional Partners:
CL1_1898
Amino acid transporter; COG0531.
 
 
 0.726
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
 
  
 
 0.713
CL1_1601
Asparagine synthase; COG0367.
 
 
 0.694
CL1_1342
Hypothetical protein containing HAD-like domain 7; COG0463.
  
 
 0.681
CL1_0996
Hypothetical protein; COG3119.
  
 
 0.679
CL1_0991
Hypothetical protein.
  
 
 0.678
CL1_0837
Hypothetical protein.
  
 
 0.672
CL1_0598
Hypothetical protein; COG0300.
 
 
 0.651
CL1_1355
Nicotinate phosphoribosyltransferase; COG1488.
   
 
 0.632
CL1_0201
NADH dehydrogenase subunit D; COG0649; Belongs to the complex I 49 kDa subunit family.
 
 
 0.591
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.