STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1360ferredoxin-NADP(+) reductase subunit alpha 1; COG0543. (280 aa)    
Predicted Functional Partners:
CL1_1359
Glutamate synthase small subunit-like protein; COG0493.
 
 0.997
CL1_1439
Putative oxidoreductase; COG0493.
 
 0.984
CL1_1144
Putative glutamate synthase subunit beta; COG0493.
 
 0.918
CL1_1440
ferredoxin-NADP(+) reductase subunit alpha 2; COG0543.
  
  
 
0.909
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
 
 
 0.893
pyrD
Putative dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.859
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
  
 0.635
pyrE
Putative orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.622
pyrB
Aspartate carbamoyltransferase catalytic subunit; COG0540.
  
  
 0.621
CL1_1361
Hypothetical protein; COG1701.
       0.606
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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