STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1361Hypothetical protein; COG1701. (260 aa)    
Predicted Functional Partners:
CL1_1196
GHMP kinase 2; COG1829.
 
  
 0.981
CL1_1885
Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; COG0452.
 
  
 0.961
mfnA
Tyrosine decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily.
 
  
 0.931
CL1_0205
4-aminobutyrate aminotransferase 1; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
CL1_0744
Putative carbon-nitrogen hydrolase; COG0388.
     
  0.900
CL1_1122
4-aminobutyrate aminotransferase 2; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
CL1_1455
Hypothetical protein; COG1931; Belongs to the UPF0201 family.
 
   
 0.633
CL1_1360
ferredoxin-NADP(+) reductase subunit alpha 1; COG0543.
       0.606
CL1_1359
Glutamate synthase small subunit-like protein; COG0493.
       0.533
nusA
Transcription elongation factor NusA-like protein; Participates in transcription termination. Belongs to the NusA family.
 
     0.526
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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