STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CL1_1362Putative transcriptional regulator; COG1709. (243 aa)    
Predicted Functional Partners:
CL1_1403
Putative 3-hydroxy-3-methylglutaryl CoA synthase-like protein; COG3425; Belongs to the thiolase-like superfamily. UPF0219 family.
  
    0.877
CL1_1405
Hypothetical protein; COG1545.
 
    0.657
CL1_0646
Hypothetical protein containing metal dependent hydrolase domain; COG1831.
  
     0.643
CL1_0880
Hypothetical protein containing SAM domain 4; COG2108.
  
     0.630
CL1_1404
acetyl-CoA acetyltransferase; COG0183.
  
    0.626
CL1_0704
Hypothetical protein; COG2237.
 
     0.586
CL1_0350
Hypothetical protein; COG1885; Belongs to the UPF0212 family.
  
     0.548
carS
Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
     0.534
CL1_0981
Hypothetical protein; COG3609.
  
   
 0.517
CL1_0386
Transcription regulator, ArsR family 5; COG1777.
  
   
 0.503
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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