Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1366Hypothetical protein; COG0446. (481 aa)    
Predicted Functional Partners:
CL1_1367
Putative ferredoxin; COG1142.
   
 0.997
CL1_1369
Hypothetical protein; COG0665.
 
 0.970
CL1_1380
Hypothetical protein; COG0665.
 
 0.952
CL1_1368
Hypothetical protein; COG0446.
 
   
 0.940
gcvT
Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.
    
 0.905
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
 
 
 
 0.618
CL1_1381
Hypothetical protein; COG0446.
 
    
0.601
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
    0.519
CL1_0424
Anaerobic glycerol-3-phosphate dehydrogenase subunit A; COG0579.
   
 0.439
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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