STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1379Galactokinase; COG0153. (353 aa)    
Predicted Functional Partners:
CL1_0826
Hypothetical protein containing oxidoreductase-domain; COG0673.
 
 
 0.699
CL1_1380
Hypothetical protein; COG0665.
  
  
 0.636
CL1_1381
Hypothetical protein; COG0446.
     
 0.633
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
  
  
0.491
CL1_0884
Cyclomaltodextrinase; COG0366.
 
  
 0.480
CL1_1915
Hypothetical protein containing KH domain; COG1094.
    
   0.476
CL1_0091
Pullulanase type II; COG0366.
 
  
 0.468
CL1_1382
Sodium:solute symporter family protein; COG0591; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
       0.444
CL1_1185
L-fuculose phosphate aldolase; COG0235.
 
   
 0.436
CL1_1378
Hypothetical protein.
       0.422
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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