STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1403Putative 3-hydroxy-3-methylglutaryl CoA synthase-like protein; COG3425; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa)    
Predicted Functional Partners:
CL1_0345
Arcaheal type Hydroxymethylglutaryl-CoA reductase; COG1257; Belongs to the HMG-CoA reductase family.
 
 0.999
CL1_1404
acetyl-CoA acetyltransferase; COG0183.
 
 0.999
CL1_1405
Hypothetical protein; COG1545.
 
 
 0.996
CL1_1249
Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; COG1014.
    
 0.918
CL1_1243
Pyruvate ferredoxin oxidoreductase subunit beta; COG1013.
    
 0.903
CL1_0008
2-oxoglutarate ferredoxin oxidoreductase subunit beta 1; COG1013.
     
 0.902
CL1_0011
2-oxoglutarate ferredoxin oxidoreductase subunit beta 2; COG1013.
     
 0.902
CL1_0009
2-oxoglutarate ferredoxin oxidoreductase subunit alpha 1; COG0674.
     
  0.900
CL1_0012
2-oxoglutarate ferredoxin oxidoreductase subunit alpha 2; COG0674.
     
  0.900
CL1_1244
Pyruvate ferredoxin oxidoreductase subunit alpha; COG0674.
    
  0.900
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.