STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1405Hypothetical protein; COG1545. (134 aa)    
Predicted Functional Partners:
CL1_1403
Putative 3-hydroxy-3-methylglutaryl CoA synthase-like protein; COG3425; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 
 0.999
CL1_1404
acetyl-CoA acetyltransferase; COG0183.
 
 
 0.999
CL1_1401
C/D box methylation guide ribonucleoprotein complex aNOP56 subunit; COG1498.
       0.748
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
       0.748
CL1_1362
Putative transcriptional regulator; COG1709.
 
    0.657
CL1_1998
Glucose-1-dehydrogenase; COG1028.
 
 
 
 0.500
CL1_1147
Hypothetical protein containing ferredoxins domain 3; COG0437.
   
  
 0.460
CL1_1356
Short-chain alcohol dehydrogenase; COG1028.
   
 
 0.433
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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