Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_1412Putative histone deacetylase; COG0123. (332 aa)    
Predicted Functional Partners:
CL1_1720
Putative Serine/threonine protein phosphatase; COG0631.
 
 0.956
tbp
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
 0.938
CL1_1071
DNA/RNA helicase, superfamily II; COG0553.
  
 0.886
CL1_1722
Hypothetical protein containing WD40 repeat; COG2319.
  
 0.818
cobB
NAD-dependent deacetylase; COG0846; Belongs to the sirtuin family. Class III subfamily.
   
 0.813
pcp
Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
    
 
 0.800
CL1_1728
Hypothetical protein; COG2319.
   
 0.794
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.753
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
   
 
 0.750
CL1_1410
Hypothetical protein; COG1542.
 
     0.710
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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