STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1412Putative histone deacetylase; COG0123. (332 aa)    
Predicted Functional Partners:
tbp
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
 0.875
CL1_1071
DNA/RNA helicase, superfamily II; COG0553.
  
 0.812
cobB
NAD-dependent deacetylase; COG0846; Belongs to the sirtuin family. Class III subfamily.
   
 
 0.761
CL1_1720
Putative Serine/threonine protein phosphatase; COG0631.
 
 0.745
CL1_0223
Putative TBP-interacting protein DNA helicase Tip49-like protein; COG1224.
  
 
 0.725
CL1_1722
Hypothetical protein containing WD40 repeat; COG2319.
  
 
 0.713
leuS
leucyl-tRNA synthetase; COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 
 0.681
CL1_1728
Hypothetical protein; COG2319.
    
 0.675
CL1_1261
D-3-phosphoglycerate dehydrogenase; COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.620
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
    
  0.617
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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