STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1414Indolepyruvate ferredoxin oxidoreductase, beta subunit 2; COG1014. (202 aa)    
Predicted Functional Partners:
CL1_1415
Indolepyruvate ferredoxin oxidoreductase, alpha subunit 2; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
 
 0.996
CL1_0679
Indolepyruvate ferredoxin oxidoreductase, alpha subunit 1; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
 
 0.933
CL1_1416
acetyl-CoA synthetase II (NDP forming) subunit alpha; COG1042.
     
 0.913
CL1_1417
Putative metal-dependent hydrolase; COG2220; Belongs to the UPF0173 family.
       0.820
CL1_1418
Hypothetical protein; COG2247.
  
    0.639
CL1_0008
2-oxoglutarate ferredoxin oxidoreductase subunit beta 1; COG1013.
  
 
 0.596
CL1_0011
2-oxoglutarate ferredoxin oxidoreductase subunit beta 2; COG1013.
  
 
 0.596
CL1_1243
Pyruvate ferredoxin oxidoreductase subunit beta; COG1013.
  
 
 0.584
CL1_1246
2-ketoisovalerate ferredoxin oxidoreductase subunit beta; COG1013.
  
 
 0.584
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
     
 0.572
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.