STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1453Hypothetical protein; COG0237; Belongs to the UPF0200 family. (185 aa)    
Predicted Functional Partners:
hel308
Ski-2 like helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
     
 0.866
CL1_1455
Hypothetical protein; COG1931; Belongs to the UPF0201 family.
    0.842
CL1_1451
Hypothetical protein.
       0.526
CL1_1361
Hypothetical protein; COG1701.
 
     0.504
CL1_0822
Hypothetical protein; COG2888.
  
     0.495
CL1_0760
Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
   
 0.478
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.472
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
       0.470
CL1_1049
Hypothetical protein; COG1938.
 
     0.432
CL1_1691
DEAD/DEAH box helicase; COG1202.
 
     0.412
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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