STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1499Hypothetical protein; COG1585. (128 aa)    
Predicted Functional Partners:
CL1_1498
Hypothetical protein; COG1451.
       0.901
cobS
Putative cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
    0.589
CL1_0032
Hypothetical protein; COG3503.
       0.583
CL1_1631
Hypothetical protein; COG1030.
  
  
 0.509
CL1_0387
Ferredoxin; COG1145.
  
   
 0.473
CL1_1896
Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family.
     
 0.424
CL1_1630
Stomatin-like protein 1; COG0330.
 
 
 0.422
CL1_1346
Putative transcription regulator, penicillinase repressor family; COG3682.
 
     0.420
polC
DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
     
 0.408
CL1_1250
Putative phosphate transporter protein; COG0306.
     
 0.408
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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