Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_1535CDP-alcohol phosphatidyltransferase; COG0558; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (188 aa)    
Predicted Functional Partners:
CL1_1536
tRNA 2'-O-methylase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
       0.916
CL1_1537
Hypothetical protein.
       0.916
CL1_1538
Hypothetical protein; COG1912.
 
     0.865
CL1_1539
Archaeal nicotinamide-nucleotide adenylyltransferase; COG1056.
 
     0.864
CL1_1474
Myo-inositol-1-phosphate synthase; COG1260.
 
   
 0.795
CL1_0125
Putative kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
     
 0.543
CL1_1807
Biotin-protein ligase; COG0340.
 
  
 0.505
CL1_0085
Competence damage-inducible protein A; COG1058; Belongs to the CinA family.
  
  
 0.501
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.495
CL1_1540
Hypothetical protein; COG0787.
       0.494
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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