Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CL1_1568Cell division protein containing CDC48 domain 1; COG0464. (795 aa)    
Predicted Functional Partners:
CL1_1590
Cell division protein containing CDC48 domain 2; COG0464.
  
  
 
0.901
CL1_1569
Small heat shock protein, Hsp20 type; COG0071; Belongs to the small heat shock protein (HSP20) family.
  
 
 0.870
CL1_1566
Hypothetical protein.
       0.854
CL1_1567
Hypothetical protein; COG2982.
       0.832
CL1_1720
Putative Serine/threonine protein phosphatase; COG0631.
  
 
 0.810
CL1_1412
Putative histone deacetylase; COG0123.
 
 
 0.690
CL1_1570
Hypothetical protein; COG1236.
 
 
   0.667
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
 
 0.506
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.495
CL1_1802
Arsenical pump-driving ATPase; COG0003.
 
 
 0.495
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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