STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif6Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (228 aa)    
Predicted Functional Partners:
rpl35ae
50S ribosomal protein L35Ae; COG2451; Belongs to the eukaryotic ribosomal protein eL33 family.
   
 
 0.999
rpl37ae
50S ribosomal protein L37Ae; Binds to the 23S rRNA.
  
 
 0.999
rpl21e
50S ribosomal protein L21e; COG2139; Belongs to the eukaryotic ribosomal protein eL21 family.
  
   0.999
CL1_0288
Putative GTP-binding protein; COG1084.
  
 
 0.999
rpl30e
50S ribosomal protein L30e; COG1911; Belongs to the eukaryotic ribosomal protein eL30 family.
  
 
 0.999
rpl15e
50S ribosomal protein L15e; COG1632; Belongs to the eukaryotic ribosomal protein eL15 family.
 
   0.999
rpl18e
Ribosomal protein L18e; COG1727; Belongs to the eukaryotic ribosomal protein eL18 family.
  
 
 0.999
rpl34e
Ribosomal protein L34Ae; COG2174; Belongs to the eukaryotic ribosomal protein eL34 family.
  
 
 0.999
rpl30
50S ribosomal protein L30; COG1841.
 
 
 0.999
rpl18
50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
 
 0.999
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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