STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1607Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (186 aa)    
Predicted Functional Partners:
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
     
 0.755
CL1_1605
Hypothetical protein; COG0656.
       0.716
CL1_1606
Hypothetical protein.
       0.716
CL1_1342
Hypothetical protein containing HAD-like domain 7; COG0463.
  
  
 0.700
CL1_1202
23S rRNA (uracil-5-)-methyltransferase 1; COG2265; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
     0.638
CL1_1604
Putative ATPase containing PIN domain; COG1855.
       0.517
CL1_1601
Asparagine synthase; COG0367.
       0.505
eif1a
Translation initiation factor IF-1; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
  
  
 0.481
CL1_0825
Pleiotropic regulatory protein, pyridoxal-phosphate-dependent aminotransferase (degT); COG0399; Belongs to the DegT/DnrJ/EryC1 family.
     
 0.457
CL1_0824
Hypothetical protein containing Trimeric LpxA-like domain; COG0110.
       0.408
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: medium (76%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.