STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1630Stomatin-like protein 1; COG0330. (281 aa)    
Predicted Functional Partners:
CL1_1631
Hypothetical protein; COG1030.
 
  
 0.939
CL1_1632
Hypothetical protein; COG2319.
       0.642
CL1_1633
Putative DNA glycosylase; COG0122.
       0.642
CL1_1628
Hypothetical protein; COG2249.
       0.573
CL1_1629
ATPase, MinD family 3; COG0455.
       0.573
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
   
 
 0.560
CL1_1634
Hypothetical protein; COG1825.
       0.532
CL1_1635
Hypothetical protein.
       0.500
CL1_1648
Integral membrane protein rhomboid-like protein; COG0705.
  
 0.496
CL1_1638
Hypothetical protein.
       0.448
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.