STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1648Integral membrane protein rhomboid-like protein; COG0705. (203 aa)    
Predicted Functional Partners:
CL1_1647
Bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase; COG0483.
 
     0.928
CL1_1646
Hypothetical protein; COG1967.
       0.916
egsA
NAD(P)-dependent glycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
  
    0.849
CL1_1644
Hypothetical protein; COG1860; Belongs to the UPF0179 family.
       0.820
upp
Putative uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
       0.654
CL1_0063
Hypothetical protein.
 
 0.567
CL1_0998
Hypothetical protein containing peptidase M50 domain 2; COG0750.
  
  
 0.554
CL1_1802
Arsenical pump-driving ATPase; COG0003.
  
   0.523
CL1_1630
Stomatin-like protein 1; COG0330.
  
 0.481
CL1_1715
Stomatin-like protein 2; COG0330.
  
 0.481
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.