STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1648Integral membrane protein rhomboid-like protein; COG0705. (203 aa)    
Predicted Functional Partners:
CL1_1647
Bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase; COG0483.
 
     0.846
CL1_1646
Hypothetical protein; COG1967.
       0.818
egsA
NAD(P)-dependent glycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
  
    0.660
CL1_1644
Hypothetical protein; COG1860; Belongs to the UPF0179 family.
       0.600
CL1_0063
Hypothetical protein.
 
 0.579
CL1_0998
Hypothetical protein containing peptidase M50 domain 2; COG0750.
  
  
 0.519
CL1_1630
Stomatin-like protein 1; COG0330.
  
 0.496
CL1_1715
Stomatin-like protein 2; COG0330.
  
 0.496
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
 
     0.445
CL1_1898
Amino acid transporter; COG0531.
  
 
 0.407
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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