CL1_1652 protein (Thermococcus cleftensis) - STRING interaction network

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Score

CL1_1652

Glutamyl aminopeptidase, M42 family; COG1363. (348 aa)

Predicted Functional Partners:

CL1_1651

0.836

sfsA

0.812

CL1_0998

0.416

pan

0.406

CL1_0151

0.402

Your Current Organism:

Thermococcus cleftensis

NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CL1_0151	CL1_1652	CL1_0151	CL1_1652	Putative ATP-dependent protease Lon; COG1067; Belongs to the peptidase S16 family.	Glutamyl aminopeptidase, M42 family; COG1363.	0.402
CL1_0151	pan	CL1_0151	CL1_1339	Putative ATP-dependent protease Lon; COG1067; Belongs to the peptidase S16 family.	Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]	0.535
CL1_0998	CL1_1652	CL1_0998	CL1_1652	Hypothetical protein containing peptidase M50 domain 2; COG0750.	Glutamyl aminopeptidase, M42 family; COG1363.	0.416
CL1_1651	CL1_1652	CL1_1651	CL1_1652	Hypothetical protein; COG4232.	Glutamyl aminopeptidase, M42 family; COG1363.	0.836
CL1_1651	sfsA	CL1_1651	CL1_1653	Hypothetical protein; COG4232.	Sugar fermentation stimulation protein A; COG1489; Belongs to the SfsA family.	0.508
CL1_1652	CL1_0151	CL1_1652	CL1_0151	Glutamyl aminopeptidase, M42 family; COG1363.	Putative ATP-dependent protease Lon; COG1067; Belongs to the peptidase S16 family.	0.402
CL1_1652	CL1_0998	CL1_1652	CL1_0998	Glutamyl aminopeptidase, M42 family; COG1363.	Hypothetical protein containing peptidase M50 domain 2; COG0750.	0.416
CL1_1652	CL1_1651	CL1_1652	CL1_1651	Glutamyl aminopeptidase, M42 family; COG1363.	Hypothetical protein; COG4232.	0.836
CL1_1652	pan	CL1_1652	CL1_1339	Glutamyl aminopeptidase, M42 family; COG1363.	Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]	0.406
CL1_1652	sfsA	CL1_1652	CL1_1653	Glutamyl aminopeptidase, M42 family; COG1363.	Sugar fermentation stimulation protein A; COG1489; Belongs to the SfsA family.	0.812
pan	CL1_0151	CL1_1339	CL1_0151	Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]	Putative ATP-dependent protease Lon; COG1067; Belongs to the peptidase S16 family.	0.535
pan	CL1_1652	CL1_1339	CL1_1652	Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]	Glutamyl aminopeptidase, M42 family; COG1363.	0.406
sfsA	CL1_1651	CL1_1653	CL1_1651	Sugar fermentation stimulation protein A; COG1489; Belongs to the SfsA family.	Hypothetical protein; COG4232.	0.508
sfsA	CL1_1652	CL1_1653	CL1_1652	Sugar fermentation stimulation protein A; COG1489; Belongs to the SfsA family.	Glutamyl aminopeptidase, M42 family; COG1363.	0.812