STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1676Multidrug ABC transporter ATPase 3; COG1131. (325 aa)    
Predicted Functional Partners:
CL1_1677
ABC type multidrug transporter permease; COG0842.
 
  
 0.964
CL1_1675
Transcription regulator, PadR-like familiy 3; COG1695.
 
    0.849
CL1_1979
Hypothetical protein; COG1277.
 
 
 0.605
nth
Hypothetical protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
     0.604
CL1_0333
Hypothetical protein; COG1277.
  
 
 0.549
CL1_1164
ABC type transporter permease 2; COG1277.
  
 
 0.549
CL1_1165
ABC type transporter permease 3; COG1277.
  
 
 0.549
CL1_1674
Cell division protein containing CDC48 domain 3.
       0.540
CL1_1160
ABC type transporter permease 1; COG0842.
 
  
 0.465
CL1_1678
Hypothetical protein.
       0.461
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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