STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1677ABC type multidrug transporter permease; COG0842. (254 aa)    
Predicted Functional Partners:
CL1_1676
Multidrug ABC transporter ATPase 3; COG1131.
 
  
 0.964
CL1_1675
Transcription regulator, PadR-like familiy 3; COG1695.
 
     0.935
nth
Hypothetical protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.646
CL1_1674
Cell division protein containing CDC48 domain 3.
       0.646
CL1_1857
ATP-binding transport protein; COG1131.
 
  
 0.622
CL1_1457
Putative ABC type transporter, ATPase; COG1131.
 
  
 0.604
CL1_1161
ABC type transporter ATPase 2; COG1131.
 
  
 0.553
CL1_1981
ABC type multidrug transporter ATPase 4; COG1131.
 
  
 0.536
CL1_1556
NAD(P)H-flavin oxidoreductase; COG0778.
  
  
 0.509
CL1_1659
Hypothetical protein; COG0778.
  
  
 0.509
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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