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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1683Metallophosphoesterase 3; COG1409. (669 aa)    
Predicted Functional Partners:
CL1_1687
iron(III) ABC transporter periplasmic protein; COG1840.
 
     0.826
CL1_1686
iron(III) ABC transporter permease; COG1178.
 
     0.797
CL1_1684
Hypothetical protein; COG2457.
       0.709
CL1_1682
Hypothetical protein.
       0.637
CL1_1685
iron(III) ABC transporter ATPase; COG3839.
 
     0.613
CL1_1446
Dipeptide ABC transporter substrate binding protein; COG0747.
 
  
 0.582
CL1_0850
Glycoside hydrolase family 57 protein; COG0366.
 
     0.483
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
     
 0.463
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
 
  
 0.450
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.431
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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