STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1708Hypothetical protein; COG1432. (170 aa)    
Predicted Functional Partners:
CL1_1709
Hypothetical protein; COG1432.
 
 
  
0.842
CL1_1710
Ca2+/Na+ antiporter; COG0530.
       0.733
purO
Putative Inosine monophosphate cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP.
  
     0.639
CL1_1711
Thiamine ABC transporter periplasmic binding protein; COG4143.
       0.563
CL1_0692
Hypothetical protein; COG1107.
  
     0.546
CL1_1707
Hypothetical protein; COG0825.
       0.526
CL1_1489
Heat shock regulator; COG1777.
  
     0.467
CL1_1152
Nucleic acid-binding protein; COG3269.
  
     0.450
cpgS
Putative cyclic 2,3-diphosphoglycerate synthetase; Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
  
     0.437
CL1_0406
Archaeal histone A; COG2036.
  
     0.428
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.