STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1720Putative Serine/threonine protein phosphatase; COG0631. (909 aa)    
Predicted Functional Partners:
CL1_1721
Putative Serine/threonine protein kinase; COG0515.
 
 0.977
CL1_1724
Putiative protein kinase 1; COG0515.
 
 0.930
CL1_1726
Putiative protein kinase 2; COG0515.
 
 0.921
CL1_1727
Putiative protein kinase 3; COG0515.
 
 0.919
CL1_1468
Hypothetical protein; COG1192.
  
  
 0.848
topA
DNA topoisomerase, type IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...]
  
 
 0.844
CL1_1614
Chromosome segregation and condensation protein ScpA-like protein; COG1354.
 
 
 0.798
CL1_1716
Hypothetical protein; COG0464.
  
 
 0.796
CL1_0748
Glycosyl transferase family 2 protein 2; COG0463.
 
 
 0.792
CL1_1898
Amino acid transporter; COG0531.
  
  
 0.775
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.