STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1722Hypothetical protein containing WD40 repeat; COG2319. (678 aa)    
Predicted Functional Partners:
tbp
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
    
 0.856
CL1_1570
Hypothetical protein; COG1236.
    
 0.827
CL1_1555
Protein-tyrosine phosphatase; COG2453.
  
 0.799
CL1_1071
DNA/RNA helicase, superfamily II; COG0553.
   
 0.750
CL1_1720
Putative Serine/threonine protein phosphatase; COG0631.
 
 
 0.740
CL1_1721
Putative Serine/threonine protein kinase; COG0515.
 
 
 0.714
CL1_1412
Putative histone deacetylase; COG0123.
  
 
 0.713
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.688
CL1_0337
Putative DNA/RNA repair helicase; COG1061.
 
 
 0.682
CL1_0440
DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.660
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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