STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1733Hypothetical protein; COG1357. (377 aa)    
Predicted Functional Partners:
CL1_1761
Hypothetical protein; COG0491.
  
 
 0.641
CL1_1938
Hypothetical protein; COG0491.
  
 
 0.641
CL1_0824
Hypothetical protein containing Trimeric LpxA-like domain; COG0110.
  
  
 0.632
CL1_1731
Hypothetical protein; COG1621.
 
     0.595
CL1_1728
Hypothetical protein; COG2319.
 
    0.592
CL1_1342
Hypothetical protein containing HAD-like domain 7; COG0463.
  
 
 0.589
CL1_1722
Hypothetical protein containing WD40 repeat; COG2319.
 
    0.549
fusA
Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
 
 0.518
CL1_0078
Hypothetical protein; COG3595.
   
   0.506
CL1_1898
Amino acid transporter; COG0531.
  
  
 0.484
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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