Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gyaRGlyoxylate reductase; COG1052. (334 aa)    
Predicted Functional Partners:
CL1_0860
Hypothetical protein; COG0647.
  
 
 0.919
CL1_0354
Putative phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.911
CL1_0451
Putative aminotransferase 2; COG0436.
  
 
 0.911
CL1_1397
Putative aminotransferase 4; COG1167.
  
 
  0.908
CL1_0118
2-hydroxyacid dehydrogenase-like protein; COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.906
CL1_1748
23S rRNA (uracil-5-)-methyltransferase 2; COG2265; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
       0.778
CL1_1482
Hypothetical protein containing ribokinase-like domain 3; COG0524.
  
  
 0.663
CL1_1780
Putative 6-pyruvoyl-tetrahydropterin synthase; COG0720.
       0.500
CL1_1747
Putative ATPase (AAA+ superfamily) 10; COG1672.
       0.440
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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