STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1766ATP-dependent helicase, lhr-like protein (lhr); COG1201. (925 aa)    
Predicted Functional Partners:
CL1_1768
Hypothetical protein; COG0137.
       0.784
vapC-8
Hypothetical protein containing PIN domain 6; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.774
CL1_1769
Major facilitator superfamily permease 13; COG0477.
 
     0.711
CL1_0790
Hypothetical protein containing phosphoesterase domain; COG1407.
 
    0.709
CL1_1770
Fe-containing alcohol dehydrogenase; COG1454.
  
    0.662
lig
ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family.
 
    0.594
CL1_1570
Hypothetical protein; COG1236.
 
    0.572
CL1_0049
Glycosyl transferase family 2 protein 1; COG1215.
     
 0.425
CL1_0745
Putative exonuclease SbcD; COG1407.
 
    0.400
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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