Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1770Fe-containing alcohol dehydrogenase; COG1454. (398 aa)    
Predicted Functional Partners:
CL1_1771
Hypothetical protein.
       0.784
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
 
   
 0.772
CL1_1766
ATP-dependent helicase, lhr-like protein (lhr); COG1201.
  
    0.662
CL1_0274
Putative pyruvate-formate lyase-activating enzyme; COG1180.
 
  
 0.601
CL1_1772
Translation initiation factor IF-2B subunit beta; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
    0.600
CL1_1898
Amino acid transporter; COG0531.
  
 
 0.570
CL1_0882
Glycogen synthase; COG0297.
   
  
 0.557
CL1_0824
Hypothetical protein containing Trimeric LpxA-like domain; COG0110.
  
  
 0.555
CL1_0817
Hypothetical protein; COG1180.
  
  
 0.541
CL1_1144
Putative glutamate synthase subunit beta; COG0493.
 
   
 0.494
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.