STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1775Hypothetical protein; COG0640. (212 aa)    
Predicted Functional Partners:
CL1_1774
Hypothetical protein; COG0517.
       0.696
albA
DNA/RNA-binding protein albA; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
 
     0.688
CL1_1006
Hypothetical protein; COG2433.
 
     0.551
CL1_0350
Hypothetical protein; COG1885; Belongs to the UPF0212 family.
  
     0.539
CL1_1646
Hypothetical protein; COG1967.
  
     0.528
CL1_0602
Hypothetical protein; COG1422.
 
     0.464
CL1_0577
Putative transcription regulator, Lrp/AsnC family; COG1522.
  
  
 0.451
CL1_0406
Archaeal histone A; COG2036.
  
   
 0.443
CL1_1777
Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
       0.442
CL1_1486
Archaeal histone B; COG2036.
  
   
 0.420
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.